The building served as Wes Maxfield's improvised laboratory for his experiments after loosing his funding and previous lab, as well as the one in a burned down clinic.
In Total Eclipse of the Heart, Wes had moved his experiments here.
In Gone Girl, Damon killed Wes. Katherine, while being in Elena's body, injected herself with a Ripper Virus.
In While You Were Sleeping, Caroline was looking for any information about the ripper virus when she encountered Enzo who claimed he had the antidote.
- Season 5