Elena and Caroline will find college to be much more difficult than they anticipated when they stumble into a class led by a hot, but not-so-nice professor who knows more about Mystic Falls than he's letting on. Does it scare anyone else that his true passion is research that he believes will help humanity?
Matt Donovan’s life is forever changed by his experiences on the road with Rebekah.
Nina about Stefan: "She [Elena] has this weird feeling something is going on. It's this cosmic connection you have with someone that you've spent so much time with and I don't know if that will go away," Dobrev says. "She knows she's in love with Damon, but she still cares for Stefan and wants to make sure he's OK ... and when she finds out what he's been through, it's not easy for her." 
Julie Plec: You have to ask yourself: Was it Katherine and Stefan that perhaps were fated and there’s another doppelganger yet to come? You never know,” Plec hedged. “The key thing is that’s what the universe supposedly says. Is the universe real? Is the universe right? Or is it just one big prophecy and it got bastardized over the years? That’s going to be part of the fun of seeing how their relationships all move forward.” 
The new villain is waiting in the wings, according to Kat Graham, who we pressed for details. "You're going to be really surprised and elated to see who the next villain is," she says. "I'm so ready for him to be the villain." So it's someone we also possibly care about? "Yes, [it's] somebody you've seen before."