Miss Gibbons's House is a house a little outside the town in the woods. It was the place where the tomb vampires stayed after they escaped from the tomb. The owner of the house was Samantha Gibbons who was compelled by Frederick to not let Damon in. After which Damon killed her.
Pearl, who was in charge, only wanted her life back, unlike Frederick who made a rebellion against her and her methods. One night he and his girlfriend Bethanne left the house and attacked Stefan and Damon, but Stefan killed her. Pearl later stabbed Frederick with a wooden spatula as a punishment. In Let The Right One In Frederick and some other vampires kidnapped Stefan and tortured him and Harper, who was loyal to Pearl and disapproved of their actions. Alaric Saltzman, Elena, and Damon had a plan to set him free. Alaric entered inside the house as a man whose car crashed and wanted to use a phone. He killed a vampire named Billy and wanted Mrs. Gibbons to let Damon in. Damon broke her neck, since she was already compelled to not invite him in by Frederick. Damon killed several vampires along with Alaric, but then Elena with a vervain dart went into the house's basement.
One vampire was coming towards her, but Damon killed him. Elena took Stefan out to the car. While Alaric and Damon were fighting against vampires, Frederick came after Elena and Stefan. He almost killed Stefan, but Elena stabbed Frederick with a vervain dart. Elena gave some blood to Stefan, so he was stronger and able to kill Frederick. Damon and Alaric exited the house, but they saw six vampires coming. Then Pearl and Anna came and the remaining vampires were kicked out by Pearl. In Blood Brothers, John Gilbert killed Pearl and Harper, when they were about to leave town, with a stake gun. Anna came home and was horrified to find them dead. What happened with the house after this is unknown.