Isobel Saitou is a character of The Vampire Diaries novel series. She is the girlfriend of Jim Bryce who first appeared in The Return: Nightfall. She is of Japanese ancestry, and her grandmother knows about kitsunes (foxes). Jim Bryce sometimes calls her "Isa-chan".
"I don't know her very well at all. What's she like? .... Well, nice. Looks a bit like you, except Asian. Shorter than you, Elena's height, but skinnier. Sort of pretty. a little shy, the quiet type, you know. sort of hard to get to know. And... nice."
Bonnie McCullough described her as smart, nice, and quiet or shy. Isobel also has a "jumpy heart".
The Return Series
After Caroline visits her, Isobel is possessed by a malach and she pierced her lip, nose, eyebrow, and ears. She damages the nerves in the eyebrow area, and it causes Bonnie to vomit. Bonnie described her aura as shattered orange with black lashings. Isobel punches Meredith in the stomach.
When Dr. Alpert arrives, it is necessary to render Isobel unconscious before she can be placed in Dr. Alpert's SUV to be taken to the hospital. Isobel later flees the car and runs through the woods with red eyes and nearly naked except for blood and mud. Isobel eventually ends up in the hospital with infections in all the piercings.
- Main article: Isobel Flemming
Isobel Saitou does not appear in the TV series. Instead, the show has Isobel Flemming, a vampire and Elena's birth mother. In the series she's one of the recurring characters, but in the book she's a minor character.