Cherie and Frank are humans who were compelled by Isobel Flemming to serve as her "minions."
Isobel told John Gilbert that Cherie was a jazz singer she found at a blues bar in Brooklyn and that Frank was a cowboy she found at a gay rodeo in Amarillo. They were used to retrieve part of the invention that Damon kept, that helps destroy the tomb vampires. They were compelled to have sexual relations with each other, because technically Frank is gay. Isobel left town with Cherie and Frank after retrieving the invention, so that the tomb vampires can be dealt with. Isobel said she was teaching them French.
Frank is briefly seen carrying Isobel's luggage to her new house. Its unknown what happens to them after that, but likely Isobel's redemption allowed them to go back to their old lives after her death.
- Season 1
- They had bite marks all over their body meaning that Isobel also uses them to feed on when she gets hungry.
- Cherie isn't seen in Know Thy Enemy but that doesn't mean she wasn't still working with Isobel.